Cytotoxic Granule Trafficking and Fusion in Synaptotagmin7-Deficient Cytotoxic T Lymphocytes

Sleiman, M; Stevens, DR; Chitirala, P; Rettig, J

Rettig, J (corresponding author), Saarland Univ, Ctr Integrat Physiol & Mol Med CIPMM, Cellular Neurophysiol, Homburg, Germany.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

Granules of cytotoxic T lymphocytes (CTL) are derived from the lysosomal compartment. Synaptotagmin7 (Syt7) appears to be the calcium sensor triggerin......

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