Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and Oocytes

Kang, M; Kim, C; Leem, J; Kim, YH; Kwon, YJ; Yoon, YN; Chae, CH; Ahn, J; Jung, KY; Oh, JS; Kim, JS

Kim, JS (corresponding author), Korea Inst Radiol & Med Sci, Div Radiat Biomed Res, Seoul 139706, South Korea.; Jung, KY (corresponding author), Korea Res Inst Chem Technol, Therapeut & Biotechnol Div, Daejeon 34114, South Korea.; Oh, JS (corresponding author), Sungkyunkwan Univ, Dept Integrat Biotechnol, Suwon 16419, South Korea.; Kim, JS (corresponding author), Univ Sci & Technol, Radiol & Med Oncol Sci, Daejeon 34113, South Korea.; Jung, KY (corresponding author), Univ Sci & Technol, Dept Med

PHARMACEUTICALS, 2021; 14 (7):

Abstract

Although microtubule-associated serine/threonine kinase-like (MASTL) is a promising target for selective anticancer treatment, MASTL inhibitors with n......

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