Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes

Gu, J; Hardy, J; Boo, I; Vietheer, P; McCaffrey, K; Alhammad, Y; Chopra, A; Gaudieri, S; Poumbourios, P; Coulibaly, F; Drummer, HE

Drummer, HE (reprint author), Burnet Inst, Virus Entry & Vaccines Lab, Life Sci, Melbourne, Vic, Australia.; Drummer, HE (reprint author), Monash Univ, Dept Microbiol, Fac Med Nursing & Hlth Sci, Clayton, Vic, Australia.; Coulibaly, F (reprint author), Mo

JOURNAL OF VIROLOGY, 2018; 92 (9):

Abstract

The hepatitis C virus (HCV) E2 glycoprotein is a major target of the neutralizing antibody (nAb) response, with multiple type-specific and broadly neu......

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