The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1

Carpentier, SJ; Ni, MJ; Duggan, JM; James, RG; Cookson, BT; Hamerman, JA

Hamerman, JA (reprint author), Benaroya Res Inst, Immunol Program, Seattle, WA 98101 USA.; Hamerman, JA (reprint author), Univ Washington, Dept Immunol, Seattle, WA 98109 USA.

SCIENCE SIGNALING, 2019; 12 (581):

Abstract

B cell adaptor for phosphoinositide 3-kinase (PI3K) (BCAP) is a signaling adaptor that activates the PI3K pathway downstream of B cell receptor signal......

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