The crucial role of single-stranded DNA binding in enhancing sensitivity to DNA-damaging agents for Schlafen 11 and Schlafen 13

Fujiwara, K; Maekawa, M; Iimori, Y; Ogawa, A; Urano, T; Kono, N; Takeda, H; Higashiyama, S; Arita, M; Murai, J

Murai, J (通讯作者)，Keio Univ, Inst Adv Biosci, Tsuruoka, Yamagata 9970052, Japan.;Murai, J (通讯作者)，Ehime Univ, Proteosci Ctr, Div Cell Growth & Tumor Regulat, Toon, Ehime 7910295, Japan.;Murai, J (通讯作者)，Ehime Univ, Grad Sch Med, Dept Biochem & Mol Genet, Toon, Ehime 7910295, Japan.

ISCIENCE, 2023; 26 (12):

Abstract

Schlafen (SLFN) 11 enhances cellular sensitivity to various DNA-damaging anticancer agents. Among the human SLFNs (SLFN5/11/12/13/14), SLFN11 is uniqu......

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