Improved Solubility and Oral Absorption of Emodin-Nicotinamide Cocrystal Over Emodin with PVP as a Solubility Enhancer and Crystallization Inhibitor

Ban, E; An, SH; Park, B; Park, M; Yoon, NE; Jung, BH; Kim, A

Kim, A (corresponding author), CHA Univ, Coll Pharm, 335 Pangyo Ro,521 CHA Bio Complex, Seongnam Si 463400, Seongnam, South Korea.

JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 109 (12): 3660

Abstract

Emodin exerts anti-inflammatory and anti-cancer effects. However, its poor water solubility limits development into a pharmaceutical product. Although......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索