Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry

Vojtek, M; Zhang, JC; Sun, JJ; Zhang, M; Chambers, I

Zhang, M; Chambers, I (通讯作者),Univ Edinburgh, Ctr Regenerat Med, Sch Biol Sci, Inst Stem Cell Res, 5 Little France Dr, Edinburgh EH16 4UU, Midlothian, Scotland.;Zhang, M (通讯作者),Guangzhou Regenerat Med & Hlth Guangdong Lab, Bioland Lab, Ctr Cell Lineage & Atlas CCLA, Guangzhou, Peoples R China.;Zhang, M (通讯作者),Guangzhou Med Univ, Affiliated Hosp 5, Guangzhou, Peoples R China.;Zhang, M (通讯作者),Guangzhou Int Bio Isl, Guangzhou Lab, 9 XingDaoHuanBei Rd, Guangzhou 510005, Guangdong, Peoples R China.

STEM CELL REPORTS, 2022; 17 (1): 35

Abstract

Primordial germ cells (PGCs) arise from cells of the post-implantation epiblast in response to cytokine signaling. PGC development can be recapitulate......

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