Ubiquitination of stalled ribosome triggers ribosome-associated quality control

Matsuo, Y; Ikeuchi, K; Saeki, Y; Iwasaki, S; Schmidt, C; Udagawa, T; Sato, F; Tsuchiya, H; Becker, T; Tanaka, K; Ingolia, NT; Beckmann, R; Inada, T

Inada, T (reprint author), Tohoku Univ, Grad Sch Pharmaceut Sci, Sendai, Miyagi 9808578, Japan.

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

Translation arrest by polybasic sequences induces ribosome stalling, and the arrest product is degraded by the ribosome-mediated quality control (RQC)......

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