Multifaceted mechanisms mediating cystine starvation-induced ferroptosis

Shi, ZN; Naowarojna, N; Pan, ZJ; Zou, YL

Zou, YL (corresponding author), Westlake Lab Life Sci & Biomed, Westlake Four Dimens Dynam Metabol Meta4D Lab, Hangzhou, Zhejiang, Peoples R China.; Zou, YL (corresponding author), Westlake Univ, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China.; Zou, YL (corresponding author), Westlake Inst Adv Studies, Inst Biol, Hangzhou, Zhejiang, Peoples R China.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

The cyst(e)ine/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis is the most frequently targeted pathway to trigger the ferroptosis cascade and s......

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