FGFR2::TACC2 fusion as a novel KIT-independent mechanism of targeted therapy failure in a multidrug-resistant gastrointestinal stromal tumor

Dermawan, JK; Vanderbilt, CM; Chang, JC; Untch, BR; Singer, S; Chi, P; Tap, WD; Antonescu, CR

Antonescu, CR (通讯作者),Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10065 USA.

GENES CHROMOSOMES & CANCER, 2022; 61 (7): 412

Abstract

Genetic alterations in FGF/FGFR pathway are infrequent in gastrointestinal stromal tumors (GIST), with rare cases of quadruple wildtype GISTs harborin......

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