Using phage-assisted continuous evolution (PACE) to evolve human PD1

Ye, XX; Tu, M; Piao, MX; Yang, L; Zhou, Z; Li, ZP; Lin, MY; Yang, ZM; Zuo, ZC

Yang, ZM; Zuo, ZC (corresponding author), Jilin Univ, Coll Plant Sci, Jilin Prov Engn Lab Plant Genet Improvement, 5333 Xian Rd, Changchun 130062, Peoples R China.

EXPERIMENTAL CELL RESEARCH, 2020; 396 (1):

Abstract

PD1/PDL1 pathway plays a critical role in cancer immune responses. The immune checkpoint inhibitors of PD1/PDL1 have been well explored and developed ......

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