Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

Zeng, X; Zhang, YD; Ma, RY; Chen, YJ; Xiang, XM; Hou, DY; Li, XH; Huang, H; Li, T; Duan, CY

Huang, H; Duan, CY (通讯作者)，Chongqing Med Univ, Dept Anaesthesiol, Affiliated Hosp 2, Chongqing 400010, Peoples R China.;Li, T (通讯作者)，Army Med Univ, Daping Hosp, Dept Shock & Transfus, State Key Lab Trauma Burns & Combined Injury, Chongqing 400042, Peoples R China.

MILITARY MEDICAL RESEARCH, 2022; 9 (1):

Abstract

Background Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that can occur when the blood supply to the ischemic brain t......

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