Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma

Chen, R; Herrera, A; Hou, J; Chen, L; Wu, J; Guo, YM; Synold, TW; Ngo, VN; Puverel, S; Mei, M; Popplewell, L; Yi, SH; Song, JY; Tao, S; Wu, XW; Chan, WC; Forman, SJ; Kwak, LW; Rosen, ST; Newman, EM

CLINICAL CANCER RESEARCH, 2020; 26 (5): 1034

Abstract

Purpose: In classical Hodgkin lymphoma, the malignant Reed-Sternberg cells express the cell surface marker CD30. Brentuximab vedotin is an antibody-dr......

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