Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey

Hohlbaum, AM; Gille, H; Trentmann, S; Kolodziejczyk, M; Rattenstetter, B; Laarakkers, CM; Katzmann, G; Christian, HJ; Andersen, N; Allersdorfer, A; Olwill, SA; Meibohm, B; Audoly, LP; Swinkels, DW; van Swelm, RPL

van Swelm, RPL (reprint author), Translat Metab Lab 830, Dept Lab Med, Geert Grootepl 10, NL-6525 GA Nijmegen, Netherlands.

BRITISH JOURNAL OF PHARMACOLOGY, 2018; 175 (7): 1054

Abstract

BACKGROUND AND PURPOSE Anaemia of chronic disease (ACD) has been linked to iron-restricted erythropoiesis imposed by high circulating levels of hepcid......

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