Crystal structure and activation mechanism of DR3 death domain

Yin, XY; Li, WQ; Ma, H; Zeng, WH; Peng, C; Li, YJ; Liu, MZY; Chen, Q; Zhou, RB; Jin, TC

Yin, XY; Jin, TC (reprint author), Univ Sci & Technol China, Med Ctr, Hefei, Anhui, Peoples R China.; Yin, XY; Jin, TC (reprint author), Univ Sci & Technol China, Sch Life Sci, CAS Key Lab Innate Immun & Chron Dis, Lab Struct Immunol, Hefei, Anhui, People

FEBS JOURNAL, 2019; 286 (13): 2593

Abstract

Death receptor 3 (DR3) (a.k.a. tumor necrosis factor receptor superfamily 25) plays a key role in the immune system by activating nuclear factor kappa......

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