Monodisperse oligoethylene glycols modified Camptothecin, 10-Hydroxycamptothecin and SN38 prodrugs

Deng, T; Mao, XL; Xiao, Y; Yang, ZG; Zheng, X; Jiang, ZX

Jiang, ZX (reprint author), Wuhan Univ, Hubei Prov Engn & Technol Res Ctr Fluorinated Pha, Wuhan 430071, Hubei, Peoples R China.; Jiang, ZX (reprint author), Wuhan Univ, Sch Pharmaceut Sci, Wuhan 430071, Hubei, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019; 29 (4): 581

Abstract

Camptothecin, which represents a class of natural products with high anticancer activity, suffers low water solubility which hampers its clinic applic......

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