Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

Galarza-Munoz, G; Briggs, FBS; Evsyukova, I; Schott-Lerner, G; Kennedy, EM; Nyanhete, T; Wang, LY; Bergamaschi, L; Widen, SG; Tomaras, GD; Ko, DC; Bradrick, SS; Barcellos, LF; Gregory, SG; Garcia-Blanco, MA

Garcia-Blanco, MA (reprint author), Duke Univ, Dept Mol Genet & Microbiol, Med Ctr, Durham, NC 27710 USA.; Garcia-Blanco, MA (reprint author), Duke Univ, Ctr RNA Biol, Durham, NC 27710 USA.; Garcia-Blanco, MA (reprint author), Univ Texas Med Branch, Dept

CELL, 2017; 169 (1): 72

Abstract

Multiple sclerosis (MS) is an autoimmune disorder where T cells attack neurons in the central nervous system (CNS) leading to demyelination and neurol......

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