Large-Scale CRISPR Screen of LDLR Pathogenic Variants

Li, MJ; Ma, LR; Chen, YW; Li, JN; Wang, YB; You, WN; Yuan, HM; Tang, XC; Ouyang, HS; Pang, DX

Tang, XC; Ouyang, HS; Pang, DX (通讯作者)，Jilin Univ, Coll Anim Sci, Anim Genome Editing Technol Innovat Ctr, Key Lab Zoonoses Res,Minist Educ, Changchun 130062, Jilin, Peoples R China.;Tang, XC; Ouyang, HS; Pang, DX (通讯作者)，Jilin Univ, Chongqing Res Inst, Chongqing 401123, Peoples R China.;Tang, XC; Ouyang, HS; Pang, DX (通讯作者)，Chongqing Jitang Biotechnol Res Inst Co Ltd, Chongqing, Peoples R China.

RESEARCH, 2023; 6 ():

Abstract

Familial hypercholesterolemia (FH) is a frequently occurring genetic disorder that is linked to early-onset cardiovascular disease. If left untreated,......

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