Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension

Ranasinghe, ADCU; Holohan, M; Borger, KM; Donahue, DL; Kuc, RD; Gerig, M; Kim, A; Ploplis, VA; Castellino, FJ; Schwarz, MA

Schwarz, MA (通讯作者),Indiana Univ Sch Med, Dept Pediat, S Bend,1234 Notre Dame Ave S, Bend, IN 46617 USA.

CIRCULATION RESEARCH, 2023; 133 (8): 704

Abstract

BACKGROUND:Epigenetic regulation of vascular remodeling in pulmonary hypertension (PH) is poorly understood. Transcription regulating, histone acetyla......

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