The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate

Li, ZL; Fang, F; Long, YT; Zhao, Q; Wang, XT; Ye, Z; Meng, TQ; Gu, XL; Xiang, WP; Xiong, CL; Li, HG

Xiong, CL; Li, HG (通讯作者),Huazhong Univ Sci & Technol, Tongji Med Coll, Inst Reprod Hlth, 13 Hangkong Rd, Wuhan 430030, Peoples R China.;Xiong, CL; Li, HG (通讯作者),Wuhan Tongji Reprod Med Hosp, 128 Sanyang Rd, Wuhan 430013, Peoples R China.

CELL AND BIOSCIENCE, 2022; 12 (1):

Abstract

Background: Human primordial germ cells (hPGCs) initiate from the early post-implantation embryo at week 2-3 and undergo epigenetic reprogramming duri......

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