Neuroprotection by eIF2 alpha-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss

Huang, HL; Miao, LQ; Liang, FS; Liu, XD; Xu, L; Teng, XY; Wang, QZ; Ridder, WH; Shindler, KS; Sun, Y; Hu, Y

Hu, Y (reprint author), Stanford Univ, Sch Med, Dept Ophthalmol, 1651 Page Mill Rd, Palo Alto, CA 94304 USA.

CELL DEATH & DISEASE, 2017; 8 ( ):

Abstract

No therapies exist to prevent neuronal deficits in multiple sclerosis ( MS), because the molecular mechanism responsible for the progressive neurodege......

Full Text Link