Tandem Substitutions in Somatic Hypermutation

Sepulveda-Yanez, JH; Saravia, DA; Pilzecker, B; van Schouwenburg, PA; van den Burg, M; Veelken, H; Navarrete, MA; Jacobs, H; Koning, MT

Koning, MT (通讯作者)，Leiden Univ, Med Ctr, Dept Hematol, Leiden, Netherlands.

FRONTIERS IN IMMUNOLOGY, 2022; 12 ():

Abstract

Upon antigen recognition, activation-induced cytosine deaminase initiates affinity maturation of the B-cell receptor by somatic hypermutation (SHM) th......

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