Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin

Hintzen, JCJ; Ma, HD; Deng, H; Witecka, A; Andersen, SB; Drozak, J; Guo, H; Qian, P; Li, HT; Mecinovic, J

Mecinovic, J (通讯作者)，Univ Southern Denmark, Dept Phys Chem & Pharm, Campusvej 55, DK-5230 Odense, Denmark.;Li, HT (通讯作者)，Tsinghua Univ, Tsinghua Peking Ctr Life Sci, Beijing Frontier Res Ctr Biol Struct, MOE Key Lab Prot Sci,Sch Med, Beijing 100084, Peoples R China.;Qian, P (通讯作者)，Shandong Agr Univ, Chem & Mat Sci Fac, Tai An, Shandong, Peoples R China.

PROTEIN SCIENCE, 2022; 31 (5):

Abstract

Actin histidine N-tau-methylation by histidine methyltransferase SETD3 plays an important role in human biology and diseases. Here, we report integrat......

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