Targeting the p300/CBP Axis in Lethal Prostate Cancer

Welti, J; Sharp, A; Brooks, N; Yuan, W; McNair, C; Chand, SN; Pal, A; Figueiredo, I; Riisnaes, R; Gurel, B; Rekowski, J; Bogdan, D; West, W; Young, B; Raja, M; Prosser, A; Lane, J; Thomson, S; Worthington, J; Onions, S; Shannon, J; Paoletta, S; Brown, R; Smyth, D; Harbottle, GW; Gil, VS; Miranda, S; Crespo, M; Ferreira, A; Pereira, R; Tunariu, N; Carreira, S; Neeb, AJ; Ning, J; Swain, A; Taddei, D; Schiewer, MJ; Knudsen, KE; Pegg, N; de Bono, JS

de Bono, JS (corresponding author), Inst Canc Res, 15 Cotswold Rd, London SM2 5NG, England.

CANCER DISCOVERY, 2021; 11 (5): 1118

Abstract

Resistance to androgen receptor (AR) blockade in castration-resistant prostate cancer (CRPC) is associated with sustained AR signaling, including thro......

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