Disulfiram-based disulfides as narrow-spectrum antibacterial agents

Sheppard, JG; Frazier, KR; Saralkar, P; Hossain, MF; Geldenhuys, WJ; Long, TE

Long, TE (reprint author), Marshall Univ, Sch Pharm, Dept Pharmaceut Sci & Res, Huntington, WV 25755 USA.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018; 28 (8): 1298

Abstract

Sixteen disulfides derived from disulfiram (Antabuse (TM)) were evaluated as antibacterial agents. Derivatives with hydrocarbon chains of seven and ei......

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