Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan

Hu, Z; Xia, B; Postnikoff, SDL; Shen, ZJ; Tomoiaga, AS; Harkness, TA; Seol, JH; Li, W; Chen, KF; Tyler, JK

Tyler, JK (reprint author), Weill Cornell Med, Dept Pathol & Lab Med, New York, NY 10065 USA.; Chen, KF (reprint author), Houston Methodist Res Inst, Dept Cardiovasc Sci, Houston, TX 77030 USA.; Chen, KF (reprint author), Weill Cornell Med, Dept Cardiotho

ELIFE, 2018; 7 ():

Abstract

Translational efficiency correlates with longevity, yet its role in lifespan determination remains unclear. Using ribosome profiling, translation effi......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索