WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

Rodriguez-Hernandez, I; Maiques, O; Kohlhammer, L; Cantelli, G; Perdrix-Rosell, A; Monger, J; Fanshawe, B; Bridgeman, VL; Karagiannis, SN; Penin, RM; Marcolval, J; Marti, RM; Matias-Guiu, X; Fruhwirth, GO; Orgaz, JL; Malanchi, I; Sanz-Moreno, V

Sanz-Moreno, V (corresponding author), Queen Mary Univ London, Barts Canc Inst, John Vane Sci Bldg,Charterhouse Sq, London EC1M 6BQ, England.; Sanz-Moreno, V (corresponding author), Kings Coll London, Randall Div Cell & Mol Biophys, New Hunts House, London SE1 1UL, England.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasi......

Full Text Link