Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis

Maruyama, T; Alam, JM; Fukuda, T; Kageyama, S; Kirisako, H; Ishii, Y; Shimada, I; Ohsumi, Y; Komatsu, M; Kanki, T; Nakatogawa, H; Noda, NN

Noda, NN (corresponding author), Inst Microbial Chem, Tokyo, Japan.

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021; 28 (7): 583

Abstract

Autophagosome biogenesis is an essential feature of autophagy. Lipidation of Atg8 plays a critical role in this process. Previous in vitro studies ide......

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