In vitro inhibition and induction of human liver cytochrome P450 enzymes by a novel anti-fibrotic drug fluorofenidone

Li, LL; Luo, X; Cheng, ZN

Cheng, ZN (corresponding author), Cent South Univ, Sch Xiangya Pharmaceut Sci, Changsha, Peoples R China.; Luo, X (corresponding author), Xiamen Univ, Affiliated Hosp 1, Sch Med, Xiamen, Peoples R China.

XENOBIOTICA, 2021; 51 (7): 745

Abstract

Fluorofenidone (AKF-PD) is an analog of pirfenidone and shows stronger antifibrotic effect and lower toxicity compared to pirfenidone in preclinical s......

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