Expression of NMNAT1 in the photoreceptors is sufficient to prevent NMNAT1-associated retinal degeneration

Brown, EE; Scandura, MJ; Pierce, EA

Pierce, EA (通讯作者),Harvard Med Sch, Ocular Genom Inst, Massachusetts Eye & Ear, Dept Ophthalmol, Boston, MA 02114 USA.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2023; 29 (): 319

Abstract

Nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) is a ubiquitously expressed enzyme involved in nuclear NAD+ pro-duction throughout the body. Ho......

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