Effects of Single Mutations on Protein Stability Are Gaussian Distributed

Razban, RM; Shakhnovich, EI

Shakhnovich, EI (corresponding author), Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA.

BIOPHYSICAL JOURNAL, 2020; 118 (12): 2872

Abstract

The distribution of protein stability effects is known to be well approximated by a Gaussian distribution from previous empirical fits. Starting from ......

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