Intra-Tumoral Activation of Endosomal TLR Pathways Reveals a Distinct Role for TLR3 Agonist Dependent Type-1 Interferons in Shaping the Tumor Immune Microenvironment

Thomas, G; Micci, L; Yang, WJ; Katakowski, J; Oderup, C; Sundar, P; Wang, X; Geles, KG; Potluri, S; Salek-Ardakani, S

Thomas, G; Salek-Ardakani, S (corresponding author), Pfizer Inc, Canc Immunol Discovery, Worldwide Res Dev & Med, San Diego, CA 92121 USA.

FRONTIERS IN ONCOLOGY, 2021; 11 ():

Abstract

Toll-like receptor (TLR) agonists have received considerable attention as therapeutic targets for cancer immunotherapy owing to their ability to conve......

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