Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia

Sun, XL; Zhu, H; Dong, Z; Liu, XW; Ma, X; Han, SS; Lu, F; Wang, P; Qian, SL; Wang, C; Shen, C; Zhao, XN; Zou, YZ; Ge, JB; Sun, AJ

Sun, AJ (reprint author), Fudan Univ, Inst Biomed Sci, Shanghai 200032, Peoples R China.; Sun, AJ (reprint author), Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Shanghai 200032, Peoples R China.; Sun, AJ (reprint author), Fudan Univ, Shanghai Inst Cardio

REDOX BIOLOGY, 2017; 13 ( ): 196

Abstract

The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusiv......

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