T-bet promotes potent antitumor activity of CD4(+) CAR T cells

Gacerez, AT; Sentman, CL

Sentman, CL (reprint author), Geisel Sch Med Dartmouth, Ctr Synthet Immun, Lebanon, NH 03756 USA.; Sentman, CL (reprint author), Geisel Sch Med Dartmouth, Dept Microbiol & Immunol, Lebanon, NH 03756 USA.

CANCER GENE THERAPY, 2018; 25 (5-6): 117

Abstract

Chimeric antigen receptor (CAR) therapy has shown promise against B cell malignancies in the clinic. However, limited success in patients with solid t......

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