Identification of targetable BRAF Delta N486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma

Wrzeszczynski, KO; Rahman, S; Frank, MO; Arora, K; Shah, M; Geiger, H; Felice, V; Manaa, D; Dikoglu, E; Khaira, D; Chimpiri, RA; Michelini, VV; Jobanputra, V; Darnell, RB; Powers, S; Choi, M

Wrzeszczynski, KO; Darnell, RB (reprint author), New York Genome Ctr, New York, NY 10013 USA.; Darnell, RB (reprint author), Rockefeller Univ, Lab Mol Neurooncol, New York, NY 10065 USA.; Darnell, RB (reprint author), Rockefeller Univ, Howard Hughes Med I

COLD SPRING HARBOR MOLECULAR CASE STUDIES, 2019; 5 (6):

Abstract

The tumor genome of a patient with advanced pancreatic cancer was sequenced to identify potential therapeutic targetable mutations after standard of c......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索