Irinotecan-gut microbiota interactions and the capability of probiotics to mitigate Irinotecan-associated toxicity

Mahdy, MS; Azmy, AF; Dishisha, T; Mohamed, WR; Ahmed, KA; Hassan, A; Aidy, SE; El-Gendy, AO

El-Gendy, AO (通讯作者),Beni Suef Univ, Fac Pharm, Microbiol & Immunol Dept, Salah Salem St, Bani Suwayf 62511, Egypt.

BMC MICROBIOLOGY, 2023; 23 (1):

Abstract

BackgroundIrinotecan is a chemotherapeutic agent used to treat a variety of tumors, including colorectal cancer (CRC). In the intestine, it is transfo......

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