Chemical Oral Cancerogenesis Is Impaired in PI3K gamma Knockout and Kinase-Dead Mice

Berta, GN; Di Scipio, F; Yang, ZQ; Oberto, A; Abbadessa, G; Romano, F; Carere, ME; Ceccarelli, A; Hirsch, E; Mognetti, B

Berta, GN (corresponding author), Univ Turin, Dept Clin & Biol Sci, Reg Gonzole 10, I-10043 Orbassano, TO, Italy.; Mognetti, B (corresponding author), Univ Turin, Dept Life Sci & Syst Biol, Via Accademia Albertina 13, I-10123 Turin, Italy.

CANCERS, 2021; 13 (16):

Abstract

We investigated the role of PI3K gamma in oral carcinogenesis by using a murine model of oral squamous carcinoma generated by exposure to 4-nitroquino......

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