pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells

Webb, BA; Aloisio, FM; Charafeddine, RA; Cook, J; Wittmann, T; Barber, DL

Barber, DL (corresponding author), Univ Calif San Francisco, Dept Cell & Tissue Biol, San Francisco, CA 94941 USA.

MOLECULAR BIOLOGY OF THE CELL, 2021; 32 (2): 131

Abstract

Many lysosome functions are determined by a lumenal pH of similar to 5.0, including the activity of resident acid-activated hydrolases. Lysosome pH (p......

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