Proteasome Inhibition Suppresses KIT-Independent Gastrointestinal Stromal Tumors Via Targeting Hippo/YAP/Cyclin D1 Signaling

Chen, T; Ni, N; Yuan, L; Xu, LL; Bahri, N; Sun, BS; Wu, YH; Ou, WB

Ou, WB (corresponding author), Zhejiang Sci Tech Univ, Coll Life Sci & Med, Zhejiang Prov Key Lab Silkworm Bioreactor & Biome, Hangzhou, Peoples R China.; Ou, WB (corresponding author), Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA.; Ou, WB (corresponding author), Harvard Med Sch, Boston, MA 02115 USA.

FRONTIERS IN PHARMACOLOGY, 2021; 12 ():

Abstract

Purpose: Gastrointestinal stromal tumors (GISTs) are the most common malignant tumor of mesenchymal origin of the digestive tract. A yet more challeng......

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