Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study

Ambrosini, G; Vorontsov, I; Penzar, D; Groux, R; Fornes, O; Nikolaeva, DD; Ballester, B; Grau, J; Grosse, I; Makeev, V; Kulakovskiy, I; Bucher, P

Bucher, P (corresponding author), Ecole Polytech Fed Lausanne, Sch Life Sci, CH-1015 Lausanne, Switzerland.; Bucher, P (corresponding author), Swiss Inst Bioinformat SIB, CH-1015 Lausanne, Switzerland.

GENOME BIOLOGY, 2020; 21 (1):

Abstract

BackgroundPositional weight matrix (PWM) is a de facto standard model to describe transcription factor (TF) DNA binding specificities. PWMs inferred f......

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