Preferential transcription of the mutated allele in NPM1 mutated acute myeloid leukaemia

Bailey, GD; Doolan, L; Baskar, A; Smith, LC; Seedhouse, CH

Seedhouse, CH (corresponding author), Univ Nottingham, Sch Med, Div Canc & Stem Cells, Blood Canc & Stem Cells,Biodiscovery Inst, Univ Pk, Nottingham NG7 2RD, England.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Nucleophosmin is commonly both over-expressed and mutated in acute myeloid leukemia (AML). NPM1 mutations are always heterozygous. In addition, NPM1 h......

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