PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

Hsu, WCJ; Wildburger, NC; Haidacher, SJ; Nenov, MN; Folorunso, O; Singh, AK; Chesson, BC; Franklin, WF; Cortez, I; Sadygov, RG; Dineley, KT; Rudra, JS; Taglialatela, G; Lichti, CF; Denner, L; Laezza, F

Laezza, F (reprint author), Ctr Biomed Engn, Ctr Addict Res, Dept Pharmacol & Toxicol, 301 Univ Blvd, Galveston, TX 77555 USA.; Laezza, F (reprint author), Mitchell Ctr Neurodegenerat Dis, 301 Univ Blvd, Galveston, TX 77555 USA.

EXPERIMENTAL NEUROLOGY, 2017; 295 ( ): 1

Abstract

Background: Cognitive impairment in humans with Alzheimer's disease (AD) and in animal models of A beta-pathology can be ameliorated by treatments wit......

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