AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial

Lawrence, DS; Youssouf, N; Molloy, SLF; Alanio, A; Alufandika, M; Boulware, DR; Boyer-Chammard, T; Chen, T; Dromer, F; Hlupeni, A; Hope, W; Hosseinipour, MC; Kanyama, C; Lortholary, O; Loyse, A; Meya, DB; Mosepele, M; Muzoora, C; Mwandumba, HC; Ndhlo

Lawrence, DS (reprint author), London Sch Hyg & Trop Med, Fac Infect & Trop Dis, Dept Clin Res, London, England.; Lawrence, DS (reprint author), Botswana Harvard AIDS Inst Partnership, Gaborone, Botswana.

TRIALS, 2018; 19 ():

Abstract

BackgroundCryptococcal meningitis (CM) is a major cause of mortality in HIV programmes in Africa despite increasing access to antiretroviral therapy (......

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