FADS1-arachidonic acid axis enhances arachidonic acid metabolism by altering intestinal microecology in colorectal cancer

Xu, CJ; Gu, L; Hu, LP; Jiang, CH; Li, Q; Sun, LC; Zhou, H; Liu, Y; Xue, HB; Li, J; Zhang, ZG; Zhang, XL; Xu, Q

Xu, Q (通讯作者),Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Gastrointestinal Surg, Shanghai, Peoples R China.;Li, J; Zhang, ZG; Zhang, XL (通讯作者),Shanghai Jiao Tong Univ, Shanghai Canc Inst, State Key Lab Oncogenes & Related Genes, Shanghai, Peoples R China.;Xue, HB (通讯作者),Shanghai Jiao Tong Univ, Div Gastroenterol & Hepatol, Shanghai, Peoples R China.;Xue, HB (通讯作者),Shanghai Jiao Tong Univ, Minist Hlth, Key Lab Gastroenterol & Hepatol, Shanghai, Peoples R China.;Xue, HB (通讯作者),Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Shanghai, Peoples R China.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Colonocyte metabolism shapes the microbiome. Metabolites are the main mediators of information exchange between intestine and microbial communities. A......

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