Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIP-mediated NLRP3 inflammasome activation

Huang, PP; Fu, J; Liu, LH; Wu, KF; Liu, HX; Qi, BM; Liu, Y; Qi, BL

Liu, Y; Qi, BL (corresponding author), Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Geriatr, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R China.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020; 45 (1): 186

Abstract

Senescence of cardiomyocytes is considered a key factor for the occurrence of doxorubicin (Dox)-associated cardiomyopathy. The NOD-like receptor famil......

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