The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction

Sayoc-Becerra, A; Krishnan, M; Fan, SJ; Jimenez, J; Hernandez, R; Gibson, K; Preciado, R; Butt, G; McCole, DF

McCole, DF (corresponding author), Univ Calif Riverside, Sch Med, Div Biomed Sci, 307 Sch Med Res Bldg,900 Univ Ave, Riverside, CA 92521 USA.

INFLAMMATORY BOWEL DISEASES, 2020; 26 (3): 407

Abstract

By conducting a series of fecal microbiota transplantation experiments, we show a variable effect on ileitis severity from human gut microbiota isolat......

Full Text Link