SPOROS: A pipeline to analyze DISE/6mer seed toxicity

Bartom, ET; Kocherginsky, M; Paudel, B; Vaidyanathan, A; Haluck-Kangas, A; Patel, M; O'Shea, KL; Murmann, AE; Peter, ME

Bartom, ET; Peter, ME (通讯作者)，Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USA.;Bartom, ET (通讯作者)，Northwestern Univ, Feinberg Sch Med, Dept Prevent Med Div Biostat, Chicago, IL 60611 USA.;Peter, ME (通讯作者)，Northwestern Univ, Feinberg Sch Med, Dept Med, Div Hematol Oncol, Chicago, IL 60611 USA.

PLOS COMPUTATIONAL BIOLOGY, 2022; 18 (3):

Abstract

microRNAs (miRNAs) are (18-22nt long) noncoding short (s)RNAs that suppress gene expression by targeting the 3' untranslated region of target mRNAs. T......

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