AI-based multi-PRS models outperform classical single-PRS models

Klau, JH; Maj, C; Klinkhammer, H; Krawitz, PM; Mayr, A; Hillmer, AM; Schumacher, J; Heider, D

Heider, D (通讯作者),Univ Marburg, Dept Math & Comp Sci, Marburg, Germany.

FRONTIERS IN GENETICS, 2023; 14 ():

Abstract

Polygenic risk scores (PRS) calculate the risk for a specific disease based on the weighted sum of associated alleles from different genetic loci in t......

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