The reduced activity of PP-1 alpha, under redox stress condition is a consequence of GSH-mediated transient disulfide formation

Singh, S; Lammle, S; Giese, H; Kammerer, S; Meyer-Roxlau, S; Alfar, EA; Dihazi, H; Guan, KM; El-Armouche, A; Richter, F

El-Armouche, A (reprint author), Tech Univ Dresden, Inst Pharmacol & Toxicol, Dresden, Germany.; Richter, F (reprint author), Goethe Univ Frankfurt Main, Funct Prote, Fac Med, Frankfurt, Germany.

SCIENTIFIC REPORTS, 2018; 8 ():

Abstract

Heart failure is the most common cause of morbidity and hospitalization in the western civilization. Protein phosphatases play a key role in the basal......

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