Insm1 regulates mTEC development and immune tolerance

Tao, WH; Ye, ZH; Wei, YQ; Wang, JX; Yang, WX; Yu, GX; Xiong, JY; Jia, SQ

Jia, SQ (通讯作者),Jinan Univ, Affiliated Hosp 1, Guangzhou, Peoples R China.;Jia, SQ (通讯作者),Jinan Univ, Guangdong Hong Kong Macao Joint Univ Lab Metab & M, Guangzhou, Peoples R China.;Jia, SQ (通讯作者),Jinan Univ, Inst Clin Med, Guangzhou, Peoples R China.;Jia, SQ (通讯作者),Key Lab Guangzhou Basic & Translat Res Pan Vasc Di, Guangzhou, Peoples R China.;Xiong, JY (通讯作者),Max Delbruck Ctr Mol Med, Helmholtz Assoc, Berlin, Germany.;Xiong, JY (通讯作者),VIB KU Leuven Ctr Canc Biol, Leuven, Belgium.

CELLULAR & MOLECULAR IMMUNOLOGY, 2023; 20 (12): 1472

Abstract

The expression of self-antigens in medullary thymic epithelial cells (mTECs) is essential for the establishment of immune tolerance, but the regulator......

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